Lysergic acid diethylamide (LSD) is the prototypical psychedelic drug, but its effects on the human brain have never been studied before with modern neuroimaging. Here, three complementary neuroimag-ing techniques: arterial spin labeling (ASL), blood oxygen level- dependent (BOLD) measures, and
Was it a vision or a waking dream? A commentary on Disrupting posterior cingulate connectivity disconnects consciousness from the external environment by Herbet, G., Lafargue, G., de Champfleur, N. M., Moritz-Gasser, S., le Bars, E., Bonnetblanc, F., et al. (2014).
Functional Connectivity Measures After Psilocybin Inform a Novel Hypothesis of Early Psychosis Psilocybin is a classic psychedelic and a candidate drug model of psychosis. This study measured the effects of psilocybin on resting-state network and thalamocortical functional connectivity (FC) using functional
The Entropic Brain – A theory of conscious states informed by neuroimaging research with psychedelic drugs Entropy is a dimensionless quantity that is used for measuring uncertainty about the state of a system but it can also imply physical qualities,
Finding the Self by Losing the Self: Neural Correlates of Ego-Dissolution Under Psilocybin Ego-disturbances have been a topic in schizophrenia research since the earliest clinical descriptions of the disorder. Manifesting as a feeling that one’s “self,” “ego,” or “I” is