Magic Mushrooms Could Be the Future of Antidepressants

We spoke to Dr. Mark Bolstridge, a clinical psychiatrist searching for alternative and unusual treatments for depression.

Bolstridge, alongside David Nutt, president of the British Neuroscience Association and former government drugs advisor, initially applied to run a psilocybin trial in 2013. Nutt had previously conducted small experiments before more stringent regulations around psychoactive substances were put into place. He felt that psilocybin had the potential to alleviate symptoms of depression and wanted to carry out further experiments.

Bolstridge is already in the process of searching for alternative and unusual treatments. In particular, he’s been looking into the hallucinogenic compound found within magic mushrooms: psilocybin.

“There are a distinct proportion of patients who don’t get better despite taking lots of different antidepressants,” says Dr. Mark Bolstridge, an honorary research associate at UCL and a clinical psychiatrist. “That’s frustrating as a clinician, that even though we do have a lot of drugs at our disposal, for some people, none of them work.”

found that some drug companies were selectively publishing studies on antidepressants that showed the drugs had a benefit and shelving others that showed there was no overall effect.

, doctors treat the causes in a crude way, with drugs “aimed at the wrong target,” often focusing on reducing stress rather than depression itself. Others have suggested that

The science of antidepressants, is not, as it goes, an exact science. Two patients can react differently to the same drug. For some people, many of the existing drugs won’t have any effect at all.

 

 


Our videos describing different aspects of what we do.

How Do Psychedelic Drugs Work On The Brain? (Full Lecture)

Can Magic Mushrooms Unlock Depression? | Rosalind Watts | TEDxOxford

Mendel Kaelen 29th June 2016

Mendel Kaelen: Psychological & Neurophysiological Effects of Music in Combination with Psychedelics

Can Magic Mushrooms treat depression?- Robin Carhart-Harris at New Scientist Live 2017

Recent Comments

  • Karl on The administration of psilocybin to healthy hallucinogen experienced volunteersI'm Karl a 40.yr Old Male who's Depressed & got Anxiety who also would like 2 try Philosybin Treatment as I don't believe in the treatment available @ the moment
  • Roxene Saviano on The administration of psilocybin to healthy hallucinogen experienced volunteersHello, I am 63 years old and am struggling with severe depression. I used many psycedelics during my teens and well into my 20s. Actually used LSD as a method of marriage communication. It was very helpful. Now 35-40 years later and nothing helps thi…
  • Robert Kew on Help us treat depression!Hi. I would very much like to participate in a trial. I'm 49 and have suffered most of my life with anxiety and depression. I'm currently on dual reuptake inhibitors but they have limited effect for me. I've tried many, many things over the years to…
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  • Bob on The administration of psilocybin to healthy hallucinogen experienced volunteersHi, I have read your articles and I am currently on anti depressants. I have tried different kinds as I have mild PTSD from military service and suffer from depression constantly. I would very much like to assist and be a volunteer for future trials.
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