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Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms

Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms

This study was approved by the National Research Ethics Service (NRES) committee London – West London and was conducted in accordance with the revised declaration of Helsinki (2000), the International Committee on Harmonisation Good Clinical Practice (GCP) guidelines and National

Author on Source October 13, 2017October 13, 2017 News Articles Read more

Can magic mushrooms treat depression? – New Scientist Live 2017

Can magic mushrooms treat depression? – New Scientist Live 2017

Could psychedelic drugs make the world a better place? In this talk, Robin Carhart-Harris will describe the rationale behind conducting the first ever clinical trial of psilocybin (magic mushrooms) as a treatment for depression – and share his results. Robin

Author on Source September 8, 2017September 8, 2017 News Articles Read more

David Nutt – The Psychedelic Crusader

David Nutt – The Psychedelic Crusader

  David Nutt The Psychedelic Crusader In a society where almost all drugs have negative associations, it’s hard to have an open and rational discussion about their potential miraculous effects. /.post__head 52 Insights David Nutt The Psychedelic Crusader • 12th/Jan/2017

Bookmarklet January 14, 2017January 14, 2017 News Articles Read more

2016’s best bits: breakthroughs in science

2016’s best bits: breakthroughs in science

From the discovery of gravitational waves to a promising male contraceptive, it was a groundbreaking year for science

The Administrator January 5, 2017January 5, 2017 News Articles No Comments Read more

Power of psychedelic drugs to lift mental distress shown in trials

In 1970 US authorities said drugs like LSD had no medical use, but two tests may just have proven that wrong

The Administrator January 5, 2017 News Articles No Comments Read more

Magic mushrooms lift severe depression in clinical trial

Magic mushrooms lift severe depression in clinical trial

Results raise hopes that active substance in class 1 drug could be used to treat mental health conditions in future

The Administrator May 17, 2016 News Articles No Comments Read more

LSD’s impact on the brain revealed in groundbreaking images

LSD’s impact on the brain revealed in groundbreaking images

First modern scans of people high on psychedelic drug has given researchers unprecedented insight into neural basis for its effects

The Administrator April 13, 2016May 12, 2016 News Articles No Comments Read more

Science Weekly podcast: David Nutt reveals the truth about drugs

Science Weekly podcast: David Nutt reveals the truth about drugs

Professor David Nutt discusses his book Drugs – Without the Hot Air, and argues that society’s prohibition of psychedelic substances is preventing groundbreaking science

The Administrator August 26, 2015October 15, 2015 Blog Read more
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Focus

The Psychedelic Research Group at Imperial focuses on two main research areas:
  1.  The action of psychedelic drugs in the brain.
  2. Their clinical utility, e.g. as aides to psychotherapy, with a particular focus on depression.
The group is lead by Dr Robin Carhart-Harris.

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Psychedelic Research Group
14 hours ago
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Imperial PRG
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Watch “Psychedelic Ceremony Study” on #Vimeo t.co/AMRy21cTDC

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17 hours ago
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I will be speaking at New Scientis Live, this September. Come along to get the latest on our DMT research. #NSLive t.co/an4AY7A9CQ

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18 hours ago
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April 19th is Bicycle Day - when Albert Hofmann became the first person to experience the psychedelic properties of… t.co/M4DhWnuioA

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1 day ago
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@DrArthurBlair And #9/20? @920Coalition

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1 day ago
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Please do share this tweet about our new surveys on general (t.co/hF4o4ZJ02v) and ceremonial use (… t.co/7TIrRG9U02

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F1000 Prime Recommendation

Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression

Roseman, L., Nutt D.J., Carhart-Harris R.


Access the recommendation on F1000Prime.

Our Papers


  • Neural correlates of the psychedelic stateNeural correlates of the psychedelic state
  • MDMA on subjective and BOLD-fMRI responses to autobiographical memoriesMDMA on subjective and BOLD-fMRI responses to autobiographical memories
  • Relative Harms and Benefits of DrugsRelative Harms and Benefits of Drugs
  • Waves of the Unconscious: The Neurophysiology of Dreamlike  PhenomenaWaves of the Unconscious: The Neurophysiology of Dreamlike Phenomena
  • Ecstasy users report different sleep to matched controlsEcstasy users report different sleep to matched controls

News Articles about us


  • Magic mushrooms may ‘reset’ the brains of depressed patientsMagic mushrooms may ‘reset’ the brains of depressed patients
  • Decoding the Tripping BrainDecoding the Tripping Brain
  • Psychedelic expert: Shrooms will be approved for depression in 10 yearsPsychedelic expert: Shrooms will be approved for depression in 10 years
  • Magic Mushrooms Could Be the Future of AntidepressantsMagic Mushrooms Could Be the Future of Antidepressants
  • Power of psychedelic drugs to lift mental distress shown in trials

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