Infographic: The Brain on Psychedelics

Infographic: The Brain on Psychedelics

Infographic: The Brain on Psychedelics Understanding how hallucinogenic drugs affect different neural networks could shed light on their therapeutic potential. © CATHERINE DELPHIAKey brain areas involved in the effects of psychedelic drugs are located in the default mode network (DMN), which is more active at rest than when attention is focused on the external environment. Neuroscientists first discovered this […]

Decoding the Tripping Brain

Decoding the Tripping Brain

© SEAN MCCABE Lying in a room at Imperial College London, surrounded by low lighting and music, Kirk experienced a vivid recollection of visiting his sick mother before she passed away. “I used to go and see my mum in the hospital quite a lot,” recalls Kirk, a middle-aged computer technician who lives in London […]

Psychedelics pioneer keeps his inner hippy in check

Psychedelics pioneer keeps his inner hippy in check

Psychedelics pioneer keeps his inner hippy in check   After giving people LSD and psilocybin, Robin Carhart-Harris is convinced of psychedelic therapy’s potential – but he daren’t get too excited about it .entry-header “I have conviction in psychedelics as tools to fundamentally understand the mind and the brain” Liz Hingley ONE of the last times […]

Psychedelic expert: Shrooms will be approved for depression in 10 years

Psychedelic expert: Shrooms will be approved for depression in 10 years

Ask a healthy person who’s tripped on psychedelics what it felt like, and they’ll probably tell you they saw sounds or heard colors: The crash-bang of a dropped box took on an aggressive,dark shape. A bright green light seemed to emit a piercing, high-pitched screech. In actuality, this “cross-wiring” — synaesthesia, as it’s known scientifically — may […]

Psilocybin for treatment-resistant depression

Psilocybin for treatment-resistant depression

Twelve people with moderate to severe treatment-resistant depression who had not responded to at least two courses of antidepressants were recruited (six men and six women, aged 30 to 64). Most of the participants actively volunteered to take part following presentations by the researchers and media coverage. Hallucinogenics such as psilocybin can cause unpleasant reactions, […]

Magic mushrooms’ effects illuminated in brain imaging studies

Magic mushrooms’ effects illuminated in brain imaging studies

The intensity of the effects reported by the participants, including visions of geometric patterns, unusual bodily sensations and altered sense of space and time, correlated with a decrease in oxygenation and blood flow in certain parts of the brain. Professor David Nutt, from the Department of Medicine at Imperial College London, the senior author of both studies, […]

Neural correlates of the LSD experience revealed by multimodal neuroimaging

Neural correlates of the LSD experience revealed by multimodal neuroimaging

Lysergic acid diethylamide (LSD) is the prototypical psychedelic drug, but its effects on the human brain have never been studied before with modern neuroimaging. Here, three complementary neuroimag-ing techniques: arterial spin labeling (ASL), blood oxygen level- dependent (BOLD) measures, and magnetoencephalography (MEG), implemented during resting state conditions, revealed marked changes in brain activity after LSD […]