Psychedelic expert: Shrooms will be approved for depression in 10 years

Psychedelic expert: Shrooms will be approved for depression in 10 years

Ask a healthy person who’s tripped on psychedelics what it felt like, and they’ll probably tell you they saw sounds or heard colors: The crash-bang of a dropped box took on an aggressive,dark shape. A bright green light seemed to emit a piercing, high-pitched screech. In actuality, this “cross-wiring” — synaesthesia, as it’s known scientifically — may […]

Psilocybin for treatment-resistant depression

Psilocybin for treatment-resistant depression

Twelve people with moderate to severe treatment-resistant depression who had not responded to at least two courses of antidepressants were recruited (six men and six women, aged 30 to 64). Most of the participants actively volunteered to take part following presentations by the researchers and media coverage. Hallucinogenics such as psilocybin can cause unpleasant reactions, […]

Magic mushrooms’ effects illuminated in brain imaging studies

Magic mushrooms’ effects illuminated in brain imaging studies

The intensity of the effects reported by the participants, including visions of geometric patterns, unusual bodily sensations and altered sense of space and time, correlated with a decrease in oxygenation and blood flow in certain parts of the brain. Professor David Nutt, from the Department of Medicine at Imperial College London, the senior author of both studies, […]

Neural correlates of the LSD experience revealed by multimodal neuroimaging

Neural correlates of the LSD experience revealed by multimodal neuroimaging

Lysergic acid diethylamide (LSD) is the prototypical psychedelic drug, but its effects on the human brain have never been studied before with modern neuroimaging. Here, three complementary neuroimag-ing techniques: arterial spin labeling (ASL), blood oxygen level- dependent (BOLD) measures, and magnetoencephalography (MEG), implemented during resting state conditions, revealed marked changes in brain activity after LSD […]

The effects of psilocybin and MDMA on between-network resting state functional connectivity

The effects of psilocybin and MDMA on between-network resting state functional connectivity

The effects of psilocybin and MDMA on between-network resting state functional connectivity in healthy volunteers Perturbing a system and observing the consequences is a classic scientific strategy for understanding a phenomenon. Psychedelic drugs perturb consciousness in a marked and novel way and thus are powerful tools for studying its mechanisms. In the present analysis, we […]

How Psilocybin Improves Your Brain

How Psilocybin Improves Your Brain

Psilocybin frees the brain from its rigid patterns and ego-driven assumptions, and allows the user to look at the world — and him or herself — from a whole new perspective. Many mushroom experiences also are accompanied by waves of good feelings and psychedelic visions of sound and color.   These results build on other […]

The Magic Effect Of Psilocybin Mushrooms

The Magic Effect Of Psilocybin Mushrooms

“These are remarkable compounds, with I think remarkable implications, if we can understand how they work and why they work,” says Roland Griffiths, a scientist at Johns Hopkins University, where some of the world’s leading psychedelic research is taking place.   Psilocybin mushrooms provoke mystical experiences and spiritual journeys when the body breaks the chemical […]

The administration of psilocybin to healthy hallucinogen experienced volunteers

The administration of psilocybin to healthy hallucinogen experienced volunteers

The administration of psilocybin to healthy,hallucinogen-experienced volunteers in a mock-functional magnetic resonance imaging environment: a preliminary investigation of tolerability This study sought to assess the tolerability of intravenously administered psilocybin in healthy, hallucinogen-experienced volunteers in a mock-magnetic resonance imaging environment as a preliminary stage to a controlled investigation using functional magnetic resonance imaging to explore […]