Broadband Cortical Desynchronization Underlies Psychedelic State

Broadband Cortical Desynchronization Underlies the Human Psychedelic State   Psychedelic drugs produce profound changes in consciousness, but the underlying neurobiological mechanisms for this remain unclear. Spontaneous and induced oscillatory activity was recorded in healthy human participants with magnetoencephalography after intravenous infusion of psilocybin—prodrug of the nonselective serotonin 2A receptor agonist and classic psychedelic psilocin. Psilocybin …

Read moreBroadband Cortical Desynchronization Underlies Psychedelic State