Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms

Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms

This study was approved by the National Research Ethics Service (NRES) committee London – West London and was conducted in accordance with the revised declaration of Helsinki (2000), the International Committee on Harmonisation Good Clinical Practice (GCP) guidelines and National Health Service (NHS) Research Governance Framework. Imperial College London sponsored the research which was conducted … Read more

Spatial Dependencies between Large-Scale Brain Networks

Spatial Dependencies between Large-Scale Brain Networks

Spatial Dependencies between Large-Scale Brain Networks Functional neuroimaging reveals both increases (task-positive) and decreases (task-negative) in neural activation with many tasks. Many studies show a temporal relationship between task positive and task negative networks that is important for efficient cognitive functioning. Here we provide evidence for a spatial relationship between task positive and negative networks. … Read more

Homological scaffolds of brain functional networks

Homological scaffolds of brain functional networks

Homological scaffolds of brain functional networks Networks, as efficient representations of complex systems, have appealed to scientists for a long time and now permeate many areas of science, including neuroimaging (Bullmore and Sporns 2009 Nat. Rev. Neurosci. 10, 186–198. (doi:10.1038/nrn2618)). Traditionally, the structure of complex networks has been studied through their statistical properties and metrics … Read more

Homological scaffolds of brain functional networks

Homological scaffolds of brain functional networks

Homological scaffolds of brain functional networks Networks, as efficient representations of complex systems, have appealed to scientists for a long time and now permeate many areas of science, including neuroimaging (Bullmore and Sporns 2009 Nat. Rev. Neurosci. 10, 186–198. (doi:10.1038/nrn2618)). Traditionally, the structure of complex networks has been studied through their statistical properties and metrics … Read more