Psychedelics as a treatment for disorders of consciousness

Abstract Based on its ability to increase brain complexity, a seemingly reliable index of conscious level, we propose testing the capacity of the classic psychedelic, psilocybin, to increase conscious awareness in patients with disorders of consciousness. We also confront the considerable ethical and practical challenges this proposal must address, if this hypothesis is to be …

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Our Focus

The Psychedelic Research Group at Imperial focuses on two main research areas:  The action of psychedelic drugs in the brain. Their clinical utility, e.g. as aides to psychotherapy, with a particular focus on depression. The group is lead by Dr Robin Carhart-Harris.

Psychedelic Surveys 2018

Please take part in our global surveys! Imperial Psychedelic Research Group are proud to launch three new exciting surveys into the use of Psychedelics. Please visit either The Psychedelic Ceremony Study, The Global Psychedelic Survey or The Microdosing Survey Study. More information can be found at The Psychedelic Survey Website. We’d appreciate it if you …

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Magic mushrooms may ‘reset’ the brains of depressed patients

  Patients taking psilocybin to treat depression show reduced symptoms weeks after treatment following a ‘reset’ of their brain activity. …     The findings come from a study in which researchers from Imperial College London used psilocybin – the psychoactive compound that occurs naturally in magic mushrooms – to treat a small number of …

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Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms

This study was approved by the National Research Ethics Service (NRES) committee London – West London and was conducted in accordance with the revised declaration of Helsinki (2000), the International Committee on Harmonisation Good Clinical Practice (GCP) guidelines and National Health Service (NHS) Research Governance Framework. Imperial College London sponsored the research which was conducted …

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Infographic: The Brain on Psychedelics

Infographic: The Brain on Psychedelics Understanding how hallucinogenic drugs affect different neural networks could shed light on their therapeutic potential. © CATHERINE DELPHIAKey brain areas involved in the effects of psychedelic drugs are located in the default mode network (DMN), which is more active at rest than when attention is focused on the external environment. Neuroscientists first discovered this …

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