Depression is a serious global problem. It’s the leading cause of disability worldwide, is linked to over half of all suicides, and affects some 350 million people. Worse still, the prevalence of depression is increasing; the World Health Organisation estimates that depression will become the leading overall contributor to the global burden of disease by 2030.
Psilocybin changes brain activity in a manner that is consistent with a large range of effective treatments for depression. More specifically, we found that circuits that are over-active and reinforced in depression become loosened and normalised under psilocybin. Psilocybin works to mimic some serotonin actions. That psilocybin does this, may explain why it may be useful in depression.
All research depends on funding and if the funds aren’t there, the research simply can’t happen.So, if you believe in our vision and conviction to try and improve the lives of patients suffering from depression, then please give us your support! This is an incredibly worthwhile cause and we are perfectly placed to deliver on it.
My depression has lifted entirely since taking part in this study. Everyone involved was so professional and kind. It is absolutely imperative that this research gets funded. It can make a massive difference to those whose lives are ruined by chronic depression. It's time that governments and society recognise this invaluable treatment.
Like everyone else who has commented so far I too think that this opportunity to explore psychedelics is both overdue but fantastic at the same time. Anything that enables us to further understand the mind and potentially assess new ways of treating/learning more about mental health illnesses is always a positive. As a female who has experienced depression and anxiety I would love to know how I can physically be of use to this great project.
Based on my own experiences, if anything has the power to help restore mental wellbeing, calm and confidence, and potentially shatter addictions, it is carefully administered hallucinogens. I am in no doubt that both LSD and psycilocibin have contributed to this relatively rapid shift in mindset and if it can benefit others I would willingly take part in any controlled research.
Professor David Nutt discusses his book Drugs – Without the Hot Air, and argues that society’s prohibition of psychedelic substances is preventing groundbreaking science
David Nutt, former government chief drugs adviser, says banning of legal highs has already been destructive to Parkinson’s and anti-smoking research
A music festival might not seem an obvious place to see and hear science, but Latitude was full of it.
For 40 years, Amanda Feilding, Countess of Wemyss and March, has believed psychedelics are an effective treatment for depression and anxiety. Now a growing number of scientists agree
Robin Carhart-Harris is the first person in the UK to have legally administered doses of lysergic acid diethylamide (LSD) to human volunteers since the Misuse of Drugs Act of 1971, and his presentation climaxes with a slide showing something no one else has seen before: an as-yet unpublished cross-sectional image of the brain of a […]
Trials of physiologically safe and non-addictive drugs such as LSD are almost impossible, writes James J H Rucker, calling on the authorities to downgrade their unnecessarily restrictive class A, schedule 1 classification Psychedelic drugs, especially lysergic acid diethylamide (LSD) and psilocybin, which is found in the Psilocybe genus of “magic” mushrooms that grow throughout the […]
Getty Images Experts say it’s hard to do research on the drugs under their current status LSD and magic mushrooms are illegal for recreational use, but some medical experts see major benefits from the drugs. In a commentary published in the journal The BMJ on Tuesday, a London-based psychiatrist argues in favor of legally reclassifying […]
To date, the project has been partially funded by Imperial College London and the Beckley Foundation. However, researchers are now in need of £25,000 to analyze scans. Scientists belief LSD (lysergic acid diethylamide) can be used to treat addictions, depression and chronic pain. So far, 20 healthy volunteers, including 15 men and 5 women, were […]
Researchers are beginning to look again at how LSD and psilocybin – the active compound in magic mushrooms – might be of benefit in the treatment of addiction, for obsessive compulsive disorder and even, according to one small Swiss study, to alleviate the symptoms of anxiety in terminally ill patients. However, writing in the BMJ, […]
It’s time to end the 50-year ban on magic mushrooms and LSD and allow potential health benefits to be explored, researchers say
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